Curriculum Vitae

I. Education

• Ph. D., University of Kentucky (2000)
• B. S., University of Kentucky (1995)

II. Industrial & Academic Experience

• Senior Research Fellow, Mayo Clinic, Jacksonville, Dept. of Neuroscience, Jacksonville, FL (2002-2004)
• Research Fellow, Mayo Clinic, Jacksonville, Dept. of Neuroscience, Jacksonville, FL (2000-2002)

III. Honors & Awards

• NSF CAREER Award Recipient (2007 - 2012)
• Excellence in Teaching Award, University of South Carolina Mortar Board Society (2007)
• American Heart Association Florida/Puerto Rico Affiliate, Postdoctoral Fellowship (2002-2004)
• Graduate School Academic Year Fellowship (Fall 1999)
• Dissertation Year Fellowship (1998-1999)
• National Science Foundation Fellowship (1995-1998)
• Commonwealth Travel Award (1998)
• Henry M. Lutes Engineering Scholarship (1991-1995)
• Chancellor Scholarship (1991-1995)

IV. Memberships

• Member of AIChE, Biomedical Engineering Society, Society for Biological Engineering, Institute of Biological Engineers, Omega Chi Epsilon, Tau Beta Pi, Golden key National Honor Society, Lambda Sigma Sophomore Honorary, Alpha Lambda Delta Freshman Honorary.

V. Publications

14. F. J. Gonzalez-Velasquez, J. A. Kotarek, and M. A. Moss (2008) "Soluble aggregates of the amyloid-β rotein selectively stimulate permeability in human brain microvascular endothelial monolayers. In Press, Journal of Neurochemistry.
13. J. A. Kotarek, K. C. Johnson, and M. A. Moss (2008) "Quartz crystal microbalance analysis of growth kinetics for aggregation intermediates of the amyloid-β protein." Analytical Biochemistry, 378: 15-24.
12. F. J. Gonzalez-Velasquez and M. A. Moss (2008) "Soluble aggregates of the amyloid-β protein activate endothelial monolayers for adhesion and subsequent transmigration of monocyte cells." Journal of Neurochemistry, 104: 500-513.
11. Michael R. Nichols, Melissa A. Moss, Dana Kim Reed, Stephanie Cratic-McDaniel, Jan H. Hoh and Terrone L. Rosenberry, "Amyloid-β protofibrils and aggregates induced in dilute hexafluoroisopropanol. Differences in stability and morphology". (In Progress) (2004).
10. Michael R. Nichols, Melissa A. Moss, Dana Kim Reed, Jan H. Hoh and Terrone L. Rosenberry, "Rapid assembly of amyloid-β peptide into unstable β-sheet fibers at a liquid/liquid interface", (Submitted, Biochemistry) (2004).
9. Melissa A. Moss, Michael R. Nichols, Dana Kim Reed, Nick Varvel and Terrone L. Rosenberry, "Nordihydroguaiaretic acid does not disaggregate β-amyloid(1-40) protofibrils but does inhibit growth arising from direct protofibril association", Molecular Pharmacology 66: 592-600 (2004).
8. Melissa A. Moss, Michael R. Nichols, Dana Kim Reed, Jan H. Hoh and Terrone L. Rosenberrry, "The peptide KLVFF-K₆ promotes β-amyloid(1-40) protofibril growth by association but does not alter protofibril effects on cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)", Molecular Pharmacology 64: 1160-1168 (2003).
7. Michael R. Nichols, Melissa A. Moss, Dana Kim Reed, Wen-Lang Lin, Rajendrani Mukhopadhyay, Jan H. Hoh and Terrone L. Rosenberry, "Growth of β-amyloid(1-40) protofibrils by monomer elongation and lateral association. Characterization of distinct products by light scattering", Biochemistry 41: 6115-6127 (2002).
6. J. Chaky, K. Anderson, M. Moss and L. Vaillancourt, "Surface hydrophobicity and surface rigidity are inducing signals for spore germination", Colletotrichum graminicola. Phytopathology 91: 558-564 (2001).
5. Melissa A. Moss and Kimberly W. Anderson, "Adhesion of cancer cells to endothelial monolayers: A study of initial attachment versus firm adhesion", The Journal of Adhesion 74: 19-40 (2000).
4. Melissa A. Moss, Stephen Zimmer and Kimberly W. Anderson, "Role of metastatic potential in the adhesion of human breast cancer cells to endothelial monolayers", Anticancer Research 20: 1425-1434 (2000).
3. Melissa Summers Moss, Betty Sisken, Steve Zimmer, and Kimberly W. Anderson, "Adhesion of nonmetastatic and highly metastatic breast cancer cells to endothelial cells exposed to shear stress", Biorheology 36: 359-371 (1999).
2. J. A. Hestekin, M. Sarkari, M. A. Summers, K. S. Ziemer and L. P. Zuba, "Conducting a graduate student symposium: Goals, guidelines, and experiences. Chemical Engineering Education Fall 1998: 266-268 (1998).
1. D. Bhattacharyya, S. Ganapathi, S. Vishwanath, M. Summers and D. A. Butterfield, "Immobilized enzyme reactions on beads and membranes", Biofunctional Membranes 117-129 (1994).

VI. Conference Proceeding - Abstracts

19. J. A. Kotarek, K. C. Johnson, and M. A. Moss. Quartz Crystal Microbalance Analysis of Growth Kinetics for Aggregation Intermediates of the Amyloid-β Protein. 2008 Annual Meeting of the Institute of Biological Engineers, Chapel Hill, NC (March 6-9, 2008).
18. F. J. Gonzalez-Velasquez and M. A. Moss. Selective activation of endothelial monolayers by soluble aggregates of the amyloid-β protein involved in Alzheimer's disease: Potential for exploitation in a cell-based biosensor. 2008 INBRE Symposium, Charleston, SC (January 17-18, 2008).
17. J. A. Kotarek and M. A. Moss. Detection of Amyloid-β Aggregate Growth using a Quartz Crystal Microbalance. 2007 Annual Meeting of the American Institute of Chemical Engineers, Salt Lake City, UT (November 4-9, 2007).
16. A. A. Reyes Barceló F. J. Gonzalez-Velasquez. and M. A. Moss. Influence of serum albumin on Alzheimer's amyloid-β protein assembly and activity. 2007 Annual Meeting of the American Institute of Chemical Engineers, Salt Lake City, UT (November 4-9, 2007).
15. F. J. Gonzalez-Velasquez, A. Reyes Barceló, and M. A. Moss. Amyloid-β induced endothelial-monocyte interactions involved in Alzheimer's disease. South Carolina Bioengineering Summit, Charleston SC (June 14-15, 2007).
14. F. J. Gonzalez-Velasquez, A. Reyes Barceló, and M. A. Moss. Amyloid-β induced endothelial-monocyte interactions involved in Alzheimer's disease. Experimental Biology 2007, Washington DC (April 28-May 2, 2007).
13. J. A. Kotarek, K. C. Johnson, and M. A. Moss. Quantification of surface-specific assembly of the amyloid-β protein involved in Alzheimer's disease using a quartz crystal microbalance. 2007 Annual Meeting of the Institute of Biological Engineers, St. Louis, MO (March 30-April 1, 2007).
12. J. A. Kotarek and M. A. Moss. Detection of active amyloid-β species using a quartz crystal microbalance. 2006 Annual Meeting of the American Institute of Chemical Engineers, San Francisco, CA (November 12-17, 2006).
11. F. J. Gonzalez-Velasquez, A. Reyes Barceló, and M. A. Moss. Amyloid-β induced endothelial-monocyte interactions involved in cerebral amyloid angiopathy and Alzheimer's disease. 2006 Annual Meeting of the American Institute of Chemical Engineers, San Francisco, CA (November 12-17, 2006).
10. F. J. Gonzalez-Velasquez, A. Reyes Barceló, and M. A. Moss. Amyloid-β induced endothelial-monocyte interactions involved in Alzheimer's disease. 2006 Biomedical Engineering Society Annual Fall Meeting, Chicago, IL (October 12-14, 2006).
9. M. A. Moss. Identification of inhibitory binding faces of β-amyloid fibril formation. 2005 Annual Meeting of the American Institute of Chemical Engineers, Cincinnati, OH, October 30-November 4.
8. M. A. Moss. Role of Αβ fibril formation in augmented monocyte recruitment to cerebrovascular endothelium. 2005 Annual Meeting of the Adhesion Society, Mobile, AL, February 19-22.
7. Michael R. Nichols, Melissa A. Moss, Dana Kim Reed, Wen-Lang Lin, Rajendrani Mukhopadhyay, Jan H. Hoh and Terrone L. Rosenberry, "Growth of β-amyloid(1-40) protofibrils by monomer elongation and lateral association", Characterization of distinct products by light scattering and atomic force microscopy. FASEB Summer Research Conference, Amyloids and Other Abnormal Protein Folding Processes, Snomass, CO (June 15-20, 2002).
1. M. A. Summers, K. W. Anderson and S. Zimmer, "Effect of TNF-α on cancer cell adhesion and metastatic potential", Biomedical Engineering Society Annual Fall Meeting, San Diego, CA (October 2-5, 1997). Annals of Biomedical Engineering (Sept/Oct 1997) S-37.
2. M. A. Summers, E. S. Leman, S. Zimmer and K. W. Anderson, "Examination of the Role of TNF-α stimulation in cancer cell adhesion using two assay types", Annual Meeting of the Institute of Chemical Engineers, Miami, FL (November 15-20, 1998).
3. M. A. Moss, S. Zimmer and K. W. Anderson, "Effect of shear stress on the adhesion of human breast cancer cells to endothelial monolayers", Annual Meeting of the Institute of Chemical Engineers, Dallas, TX (October 31-November 5. 1999).
4. Kimberly W. Anderson and Melissa Moss, "Role of cell adhesion in cancer metastasis", Proceedings of the 23rd Annual Meeting of the Adhesion Society, Myrtle Beach, SC (February 20-23, 2000).
5. M. Moss and K. Anderson, "Adhesion vs. lodging in cancer cell metastasis", Experimental Biology, Sponsored by the National American Society of Biorheology, San Diego, CA (April 15-18, 2000).
6. Melissa A. Moss, Michael R. Nichols, Dana Kim Reed and Terrone L. Rosenberry, "Effect of monoclonal antibodies on Aβ fibril formation", Experimental Biology, Sponsored by the American Society for Biochemistry and Molecular Biology, Orlando, FL (March 30-April 1, 2001).